Andrew E. Maclean

This study shows doxycycline inhibits apicoplast and mitochondrial translation in Plasmodium falciparum and Toxoplasma gondii, reducing protein abundance and mitochondrial complex IV activity.

This study characterizes mitochondrial complex composition in Perkinsus marinus, revealing conserved divergent features shared with apicomplexan parasites.

This study identifies and characterizes the Toxoplasma gondii ABCB7 homolog, showing its essential role in cytosolic iron-sulfur cluster biogenesis and protein translation.

This study shows that Plasmodium falciparum complex III is essential for asexual stage survival and gametocyte maturation, supporting its role as a drug target.

The paper identifies a new Toxoplasma gondii mitochondrial ribosomal protein essential for mitochondrial translation through in silico screening and experimental validation.