Linh T. Trinh

Orion, an AI agent, automates biomedical image analysis by integrating large language models with software execution and reasoning, generating research reports and hypotheses from imaging data.

SpatialAgent integrates large language models with dynamic tool retrieval, multimodal interpretation, and claim verification to automate end-to-end spatial biology workflows from gene-panel design to tissue annotation and hypothesis generation.

The paper introduces NSC-seq, a CRISPR-based molecular clock to track temporal and clonal events in development and precancer, revealing polyancestral initiation in colonic precancers.