Lucian Li

The paper argues that high-throughput expression datasets are underpowered due to insufficient biological replicates and recommends at least six per condition to improve reliability.

ModelMatcher connects researchers, clinicians, and stakeholders in rare disease research to accelerate translational studies and collaborations.

The paper aggregates and analyzes MeCP2 transcriptome data to identify a core set of perturbed genes and provides insights into MeCP2 function through a web portal.