Ana Paula Luiz

The paper identifies analgesic targets in mouse sensory neurons by analyzing translatomes in somata and terminals under different pain conditions.

The paper identifies how the FAAH-OUT lncRNA regulates FAAH expression through DNA methylation and enhancer activity, linking it to pain insensitivity.

This study shows pregabalin reduces cold allodynia caused by oxaliplatin by silencing specific sensory neurons through the 2{delta}-1 subunit of voltage-gated calcium channels.

The paper investigates changes in bone-innervating afferents in cancer-induced bone pain using calcium imaging and retrograde labeling, finding altered excitability in cutaneous afferents but not bone marrow afferents.

This study identifies opioid-dependent inhibition of neurotransmitter release as the primary mechanism of analgesia in NaV1.7 null mutants in mice and humans.

The paper identifies silent cold-sensing neurons that become active in neuropathic pain and contribute to cold allodynia through peripheral sensitization.

This study shows that Nav1.7 from sensory neurons affects dorsal horn neuron excitability, with functional effects not predicted by mRNA levels.