Author
The University of MelbourneORCID 0000-0002-9475-1440Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Ashley J. Ovens, Muhammad N.H. Khabib, Dingyi Yu…·Christopher G. Langendorf
This study identifies an autoinhibitory mechanism in the N-terminal extension of AMPKγ3 that regulates basal activity in skeletal muscle, offering a target for T2DM therapies.
Michael F. Sharp, Yi Sing Gee, Jennii Luu…·Wayne Crismani
The paper identifies a druggable metabolite binding site in the FA E3 ligase complex that inhibits its activity and selectively kills BRCA1-deficient cells.
Feng Yan, Jafar S. Jabbari, Naomi X.Y. Ling…·Shiang Yong Lim
The paper uses long-read sequencing to map Drp1 transcript variants in human and mouse tissues, revealing tissue-specific expression and isoform-dependent mitochondrial fission activity.
Leonit Kiriaev, Jonathan S. Oakhill, Chrystal F. Tiong…·Naomi X.Y. Ling
This paper refines a radiolabelled assay for measuring glycogen phosphorylase activity in skeletal muscle, revealing sex-specific variations and improving assay reliability across mouse strains.
Jung Ok Lee, Hye Jeong Lee, Yong Woo Lee…·Hyeon Soo Kim
This study shows that metrnl improves glucose tolerance in type 2 diabetes by activating the AMPK pathway and enhancing GLUT4 transcription.