Cancer BiologyCommunications BiologyPeer-reviewed
Frequency-dependent selection of neoantigens fosters tumor immune escape and predicts immunotherapy response
Shaoqing Chen, Duo Xie, Zan Li…·Da Zhou
This study introduces negative frequency-dependent selection (NFDS) in tumors, showing it leads to immune evasion and poor response to immunotherapy, supported by whole-exome sequencing data.
13 citations