Bertrand Beckert

This study determines the structure of paenilamicin PamB2 bound to stalled ribosomes, revealing its mechanism as a context-specific translocation inhibitor of protein synthesis.

This study identifies YlmH as a novel RQC factor in B. subtilis, showing it can replace RqcP in polyalanine tail addition and is conserved in bacteria lacking RqcP.

The paper shows JetABCD SMC complexes restrict small circular plasmids by cleaving them, while linear plasmids are not restricted, and presents a structural model for this process.

This study identifies eEF3's role in promoting tRNA dissociation from the E site during translation elongation in fungi, revealing structural insights into the yeast translation cycle.

The paper identifies ResQ as a release factor-dependent ribosome rescue factor in Bacillus subtilis, showing it is essential for growth and functions by recruiting RF2 to stalled ribosomes.

The paper presents cryo-EM structures of hibernating 70S and 100S ribosomes from E. coli, revealing the roles of HPF and RMF in ribosome inactivation and dimerization.