Molecular BiologybioRxivPreprint
IL-18 inhibition enlarges lesions, necrotic cores and thickens fibrous caps in Jak2V617F clonal hematopoiesis-driven atherosclerosis.
Mojdeh S. Tavallaie, Cheng-Chieh Hsu, Brian D. Hardaway…·Alan R. Tall
This study shows that IL-18 inhibition increases atherosclerosis lesions and necrotic cores in Jak2V617F clonal hematopoiesis mice, despite improving fibrous cap thickness.
DOI 10.1101/2025.06.03.657754