Author

Joan Jacob

The University of Texas Health Science Center at HoustonORCID 0000-0002-9756-8449Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Kendra S. CarmoniD· 2 shared Ali AzhdariniaiD· 1 shared Cara Guernsey-BiddleiD· 1 shared Ha Tran· 1 shared Julie Haewon RoweiD· 1 shared Kyoji TsuchikamaiD· 1 shared Liezl E. FranciscoiD· 1 shared Ling WuiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

Kendra S. CarmonORCID

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2 papers

Recent·Most cited

Cancer BiologyCancer ResearchPeer-reviewedDec 18, 2024

Antibody-Drug Conjugates Targeting the EGFR Ligand Epiregulin Elicit Robust Anti-Tumor Activity in Colorectal Cancer

Joan Jacob, Yasuaki Anami, Peyton C. High…·Kendra S. Carmon

This study develops and tests EREG-targeting ADCs showing efficacy in both RAS mutant and wildtype CRC, with high potency and safety in preclinical models.

21 citations

humanmouse

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Molecular BiologyJournal of Biological ChemistryPeer-reviewedJan 1, 2021

Anti-GPR56 monoclonal antibody potentiates GPR56-mediated Src-Fak signaling to modulate cell adhesion

Treena Chatterjee, Sheng Zhang, Tressie A. Posey…·Kendra S. Carmon

This study identifies an anti-GPR56 monoclonal antibody that enhances Src-Fak signaling and cell adhesion through a novel extracellular domain-dependent mechanism.

30 citations

humanexperimental assay

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