Shan Sun

This study solves cryo-EM structures of phycobilisomes from Gloeobacter violaceus under different light conditions, revealing unique proteins and structural adaptations for light intensity changes.

This study identifies acepromazine as a compound that selectively degrades multimeric proteins via TRIM21 activation, offering a new strategy for targeting disease-related protein assemblies.

This paper identifies a zebrafish vps4a mutation causing sensorimotor defects by reducing Vps4a ATPase activity and exosome biogenesis, affecting specific reflexes and vision.

The paper develops a method called STAgSPA to determine the in situ structure of a cyanobacterial PBS-PSII supercomplex at 3.5 Å resolution, revealing energy transfer mechanisms and structural coupling.