Karthik Pullela

Vi-TIS improves TIS accuracy by excluding dead cells using PMA, enhancing essential gene identification and revealing new antibiotic susceptibility patterns in E. coli.

The paper identifies new protein-coding sequences in E. coli using transposon mutagenesis and translation reporters, revealing previously unannotated genes.

This study identifies shared molecular mechanisms regulating quiescence in neural and glioma stem cells and suggests TGF-β inhibition as a potential therapeutic strategy.