Adam F. Cunningham

This study uses transposon mutagenesis in E. coli to identify genes affecting streptomycin susceptibility, revealing SbmA's role in aminoglycoside uptake.

Vi-TIS improves TIS accuracy by excluding dead cells using PMA, enhancing essential gene identification and revealing new antibiotic susceptibility patterns in E. coli.

This study characterizes SeaB, a Type 5a secretion system protein in Salmonella enterica, showing its role in biofilm formation, virulence, and protective immunity in a mouse model.

The paper identifies that a high IgG2:IgG3 antibody ratio inhibits complement-mediated killing of Neisseria gonorrhoeae, revealing a mechanism for bacterial resistance.

This study shows that antibodies alone can limit Salmonella infection, but their effectiveness is enhanced by complement and macrophages.

The paper examines how CD28+ CD8+ T cells in COVID-19 patients influence mycobacterial growth inhibition.

This study identifies discrete inflammatory signatures driving thrombosis in the spleen and liver after Salmonella infection, revealing both organ-specific and shared mechanisms.

This study shows maternal type 2 immunity, independent of antigen exposure, transfers protective immunity to offspring via microchimeric cells.

This study compares antibody responses in haemodialysis patients after vaccination with different platforms, finding mRNA vaccines induce better functional responses than viral vectors.

This study uses transposon mutagenesis to identify differential essential pathways in Salmonella Typhimurium strains SL1344 and SL3261, linking iron starvation, DNA synthesis, and membrane integrity.

This study shows that OMVs with different O-antigen lengths induce similar protection against Salmonella infections, and boosting enhances cross-protection.

TraDIS-validate is a method to validate ordered gene-replacement libraries, achieving 99.7% accuracy in identifying correct kanamycin cassette positions in the Keio library.

This study shows that MCE domains in Salmonella Typhimurium are essential for bile resistance and virulence, not for cell entry or adherence.