Molecular BiologybioRxivPreprint
Programmable RNA writing with trans-splicing
Cian Schmitt-Ulms, Alişan Kayabölen, Marcos Manero-Carranza…·Omar O. Abudayyeh
This paper introduces PRECISE, a method for programmable RNA editing that enables precise insertion, substitution, and deletion of RNA sequences in pre-mRNAs, with high efficiency and fidelity.