Bernhard Spengler

The paper shows that sleep pressure in Drosophila is regulated by a voltage-gated lipid peroxidation memory involving KV channel beta-subunits and NADPH cofactors.

The paper evaluates spatial metabolomics protocols and technologies, showing extensive metabolite coverage and comparable results across imaging MS methods.

The paper introduces metaFISH, a spatial metabolomics pipeline that links host and microbial metabolites in situ, revealing metabolic adaptations and novel symbiosis metabolites in deep-sea mussels.

An open-source cloud engine annotates imaging mass spectrometry data at controlled false discovery rate; publicly shared results reached over 3200 datasets and 6 million metabolite images by January 2019.