Author
Cancer Research UK Scotland InstituteORCID 0000-0003-0198-8244Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Shania M. Corry, Svetlana S. Sakhnevych, Noha Ehssan Mohamed…·Philip D. Dunne
This study shows that poly(I:C) treatment in CMS4 colorectal tumors induces a pro-inflammatory, CMS1-like regenerative state and identifies biomarkers for predicting therapeutic response.
Patricia P. Centeno, Christopher Chester, Georgios Kanellos…·Owen James Sansom
This study identifies SOX2 as a key driver of rapid tumorigenesis from a previously resistant skin cell population in mice, with implications for human cutaneous squamous cell carcinoma.
Eoghan J. Mulholland, Hayley L. Belnoue-Davis, Gabriel N. Valbuena…·Simon John Leedham
Pathological epithelial GREM1 expression induces therapeutically reversible ectopic stem cell niches through stromal remodelling.
Joseph A. Waldron, Georgios Kanellos, Rachael C.L. Smith…·Owen James Sansom
This study shows eIF4A1 is critical for supporting translational demands in Wnt-driven colorectal cancers, while eIF4A2 loss accelerates tumourigenesis, and eFT226 inhibits eIF4A1 function in these models.