Transcriptional remodeling by OTX2 directs specification and patterning of mammalian definitive endoderm
Ly-Sha Ee, Daniel Medina-Cano, Christopher M. Uyehara…·Matthias Stadtfeld
This study identifies OTX2 as a critical regulator of definitive endoderm specification and gut patterning through chromatin remodeling and signaling pathway regulation.