Willem A. Velema

The paper introduces SHARCLIP to map RNA-RNA, RNA-protein, and protein-protein contacts in cells, revealing structural mechanisms of splicing and therapeutic targets.

The paper uses photoaffinity labelling to investigate pantothenamide uptake differences between male and female malaria gametocytes, finding no significant uptake differences but potential subcellular localization variation.

The paper maps RNA secondary structure ensembles in living E. coli cells, identifying conserved structural elements and cold shock-responsive RNA thermometers.

This study conjugates synthetic siderophores to antisense oligomers to deliver them into bacteria, showing potent antibacterial effects without mammalian toxicity.

The paper introduces PARIS2, a method for efficiently analyzing RNA structures and interactions in cells, revealing new insights into viral RNA conformations and translation mechanisms.