Namrata Chaudhari

This study explores how oligonucleotide design affects G4 ligand-conjugated oligonucleotide binding and stabilization of G-quadruplex structures.

This study identifies redox-dependent dimerization of PolDIP2 and a conserved ApaG-domain motif critical for CHCHD2 interaction, revealing structural features governing its mitochondrial function.

The paper develops a method to selectively target and stabilize individual G4 DNA structures using ligand-conjugated oligonucleotides, demonstrating specificity without affecting off-target G4 formations.