Takeshi Wakasa

This study shows that shortening the G2 phase enhances cell death from DNA replication stress-inducing drugs, regardless of p53 status.

This study shows IAP antagonists induce apoptosis in senescent tumor cells both with and without TNF, suggesting they can eliminate TIS cells and sensitize non-senescent cells through TNF.

This study shows that trifluridine induces aberrant mitosis and cytotoxicity in both p53-null and p53-GOF mutant cells, independent of p53 function.