Author

Yan Luo

Mayo ClinicORCID 0000-0003-0338-0371Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Yan Luo3 papers · Regenerative Immunotherapy & CAR-T Translational Research Program, Department of Cancer Biology, Mayo Clinic Jacksonville, FL, USA.;

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Martha E. GaddiD· 2 shared Mohamed A. Kharfan‐DabajaiD· 2 shared Tanya HundaliD· 2 shared Yaqing Qie· 2 shared Aleeshba N. BasiliD· 1 shared Alfredo Quiñones‐HinojosaiD· 1 shared Andrew David BrimiD· 1 shared C. Burcin TaneriD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersCancer Biology

Martha E. GaddORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintNov 22, 2024

Single CAR-Dual target: Intracranial Delivery of Anti-PD-L1 CAR T Cells Effectively Eradicates Glioma and Immunosuppressive Cells in the Tumor Microenvironment.

María José Ulloa-Navas, Yan Luo, Jesus Emiliano Sanchez-Garavito…·Alfredo Quiñones‐Hinojosa

This study develops a PD-L1-targeting CAR T cell therapy, MC9999, which effectively eradicates glioblastoma and immunosuppressive cells in the tumor microenvironment through intracranial delivery.

1 citation

humanbulk RNA-seq

𝕏 PostBluesky

ImmunologyKidney InternationalPeer-reviewedApr 2, 2024

CAR T-cell therapy- Paving the way for sensitized kidney transplant patients.

Tambi Jarmi, Yan Luo, Rose Mary Attieh…·Hong Qin

This paper explores using CAR T-cells targeting BAFF-R to treat sensitized kidney transplant patients, showing cytotoxicity against autologous B cells and paving the way for clinical trials.

21 citationstop 2%

humanexperimental assay

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