NeurosciencebioRxivPreprint
RNA Editing of DEGS1 Links Genetic Risk to Ceramide Dysregulation and Astrocyte Toxicity in ALS
DOI 10.64898/2026.09.17.752108
Author
Disha Sood
Sanofi (France)ORCID 0000-0003-0405-034XUnclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2019-2026 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 20 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship4 papers
Recent·Most cited
- NeuroscienceCommunications BiologyPeer-reviewed
Unravelling neuronal and glial differences in ceramide composition, synthesis, and sensitivity to toxicity
John J. McInnis, Disha Sood, Lilu Guo…·James C. Dodge
The paper shows human iPSC-derived neurons and glia differ in ceramide synthesis, composition, and toxicity sensitivity, linking these differences to inflammation, ER stress, and apoptosis.
32 citationstop 4% - NeurosciencebioRxivPreprint
Glial state changes and neuroinflammatory RIPK1 signaling are a key feature of ALS pathogenesis
Matija Zelic, Anna S. Blazier, Fabrizio Pontarelli…·Timothy R. Hammond
This study identifies glial state changes and RIPK1 signaling as key features of ALS pathogenesis, showing that blocking RIPK1 delays disease onset and modulates glial responses.
- Developmental BiologyScientific ReportsPeer-reviewed
Functional maturation of human neural stem cells in a 3D bioengineered brain model enriched with fetal brain matrix
Disha Sood, Dana M. Cairns, Jayanth M. Dabbi…·David Lee Kaplan
This study shows that using fetal brain matrix in 3D cultures enhances the functional differentiation of human neural stem cells into neurons and astrocytes.
70 citationstop 2%