PhysiologyeLifePeer-reviewed
Genetic code expansion, click chemistry, and light-activated PI3K reveal details of membrane protein trafficking downstream of receptor tyrosine kinases
Duk‐Su Koh, Anastasiia Stratiievska, Subhashis Jana…·Sharona E. Gordon
The paper uses optogenetic PI3K activation and genetic code expansion to study RTK signaling, showing PI3K alone can traffic TRPV1 and insulin receptors to the plasma membrane.
11 citations