Tomohiko Taguchi

The paper identifies TRPM8 as an ion channel regulated by phospholipid asymmetry and shows that cytoplasmic phosphatidylserine is required for its function.

The paper shows that modified adenosines from RNA catabolism are sequentially metabolized to prevent toxicity and maintain metabolic balance.

The paper uses a non-toxic SM probe to show dynamic SM and cholesterol domains in the cytosolic leaflet of plasma membranes.

This study identifies the PI(3,5)P2/ESCRT-III axis as essential for STING degradation via lysosomal microautophagy, preventing sustained type I interferon responses.