Shahryar Khattak

This study generates human pluripotent stem cell-derived AVN-like pacemaker cells that replicate AVN function in vivo, suggesting their potential as biological conduction bridges for treating AV block.

This study evaluates natural deep eutectic solvents (NADES) as biocompatible RNA storage media, showing they preserve RNA integrity and cell viability across a range of temperatures.

This study shows that PARP1/2-mediated PARylation regulates HuR's nuclear localization, cleavage, and pro-apoptotic function by binding to the HuR-PBS motif.

This study identifies signaling pathways that enable the unlimited expansion of human pancreatic progenitors in defined conditions, leading to efficient and reproducible cell production for diabetes research and therapies.

The paper uses RNAi screens in isogenic human stem cells to identify SMARCA4 as a differential regulator of stemness and differentiation in hematopoietic and neural stem cells.