Author

Àlvaro Aytés

Columbia University Irving Medical CenterORCID 0000-0003-0725-5340Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Adrià Bernat‐PegueraiD· 1 shared Agnès Figueras· 1 shared Alberto VillanuevaiD· 1 shared Alessandro VasciaveoiD· 1 shared Álvaro LahigueraiD· 1 shared Andrea CalifanoiD· 1 shared Andrés Méndez‐LucasiD· 1 shared Brennan Chu· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Adrià Bernat‐PegueraORCID

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2 papers

Recent·Most cited

Cancer BiologyBiomedicine & PharmacotherapyPeer-reviewedMar 10, 2026

A rise in double-strand breaks sensitizes tumours to oxidative metabolism inhibitors

Ferran Medina‐Jover, Agnès Figueras, Núria Gendrau‐Sanclemente…·Francesc Viñals

The paper shows that double-strand breaks (DSBs) induce a metabolic shift towards oxidative metabolism in tumors, making them more sensitive to oxidative metabolism inhibitors.

DOI 10.1016/j.biopha.2026.119184

experimental assaycancer & tumor microenvironment

𝕏 PostBluesky

BioinformaticsCellPeer-reviewedJan 1, 2021

A Modular Master Regulator Landscape Determines the Impact of Genetic Alterations on the Transcriptional Identity of Cancer Cells

Evan Paull, Àlvaro Aytés, Sunny J. Jones…·Andrea Califano

The paper identifies 407 Master-Regulator proteins that canalize cancer genomics into transcriptional subtypes and links genetic alterations to tumor biology through modular regulatory architectures.

137 citationstop 1%

humanbulk RNA-seq

𝕏 PostBluesky