Author

Philip Vincent Charlton

University of OxfordORCID 0000-0003-0752-1960Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genomics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Francesca Meteora BuffaiD· 2 shared Adam Enver FramptoniD· 1 shared Alastair D.G. LambiD· 1 shared Alessandro BarberisiD· 1 shared Alexander V. RatushnyiD· 1 shared Ana MiariD· 1 shared Ashwin JainarayananiD· 1 shared Assaf MageniD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersGenomics

Francesca Meteora BuffaORCID

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3 papers

Recent·Most cited

ImmunologyNature CommunicationsPeer-reviewedFeb 6, 2025

Single-cell immune multi-omics and repertoire analyses in pancreatic ductal adenocarcinoma reveal differential immunosuppressive mechanisms within different tumour microenvironments

Shivan Sivakumar, Ashwin Jainarayanan, Edward H. Arbe-Barnes…·Rachael J. M. Bashford-Rogers

The paper analyzes single-cell immune multi-omics data from PDAC to identify differential immunosuppressive mechanisms in distinct tumour microenvironments.

74 citationstop 1%

humanscRNA-seq

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GenomicsbioRxivPreprintSep 4, 2023

Molecular analysis of archival diagnostic prostate cancer biopsies identifies genomic similarities in cases with progression post-radiotherapy, and those with de novo metastatic disease.

Philip Vincent Charlton, Dawn O’Reilly, Yiannis Philippou…·Richard J. Bryant

DOI 10.1101/2023.09.04.555868

humanbulk RNA-seq

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Cancer BiologybioRxivPreprintJun 23, 2022

Reconstructing the functional effect of TP53 somatic mutations on its regulon using causal signalling network modelling

Charalampos P. Triantafyllidis, Alessandro Barberis, Ana Miar…·Francesca Meteora Buffa

The paper uses network modeling to analyze how TP53 mutations affect gene regulation across cancer types and samples.

DOI 10.1101/2022.06.23.497293

humanbulk RNA-seq

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