Christian Löw

This study identifies substrate specificity of bacterial ACS transporters using genetics, biochemistry, and structural biology, revealing structural determinants of stereoselectivity in LgoT.

The paper introduces a model-free method to analyze diffusion-based single-molecule FRET experiments, showing it accurately captures protein dynamics without artifacts from photon trajectory length or diffusion.

The paper identifies MFSD1 as a lysosomal dipeptide uniporter that facilitates the transport of cationic and neutral dipeptides when amino acid exporters are overloaded.

This study determines the cryo-EM structures of the human thiamine transporter SLC19A3 in complex with ligands, revealing its transport mechanism and drug interactions.

The paper investigates six membrane transporters in Plasmodium falciparum, finding four essential for asexual development and one essential for gametocytogenesis.