Author

Steven L. Gonias

University of California San DiegoORCID 0000-0003-0843-4607Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Gail Funk· 2 shared Aaron TraniD· 1 shared Alexander J. RajiciD· 1 shared Binita Poudel· 1 shared Carlotta ZampieriiD· 1 shared Christina J. SigurdsoniD· 1 shared Daniel B. McClatchyiD· 1 shared Daniel Ojeda-JuáreziD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersNeuroscience

Gail Funk

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintAug 25, 2026

Peripheral nerve-derived extracellular vesicles are dynamically regulated in chemotherapy-induced painful peripheral neuropathy

Miles Vecchitto, Gail Funk, Zixuan Wang…·Wendy Campana

The paper identifies and characterizes Schwann cell-derived extracellular vesicles in chemotherapy-induced neuropathy, showing changes in their proteome and function.

DOI 10.64898/2026.08.20.746051

mouseexperimental assay

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NeurosciencebioRxivPreprintApr 1, 2025

PrPC-induced signaling in human neurons activates phospholipase Cγ1 and an Arc/Arg3.1 response

Daniel Ojeda-Juárez, Gail Funk, Emily Richards…·Christina J. Sigurdson

The paper shows that PrPC ligands in human neurons trigger PLCγ1 signaling and an Arc/Arg3.1 response, indicating neuronal hyperactivity in prion disease.

1 citation

humanbulk RNA-seq

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Cell BiologybioRxivPreprintOct 6, 2023

LRP1 Triggers Pro-inflammatory Cell-signaling in Response to Extracellular Tau Independently of the NMDA Receptor

Pardis Azmoon, Elisabetta Mantuano, Binita Poudel…·Steven L. Gonias

This paper shows that extracellular Tau activates pro-inflammatory signaling via LRP1 in macrophages, microglia, and astrocytes, independent of the NMDA receptor.

2 citations

mouseproteomics

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