Hongyan Hao

The paper determines the structure of VPS13C using cryo-EM, revealing a lipid-transfer-nonpermissive conformation and identifying calmodulin as a regulatory partner.

This study shows that neuronal β-spectrin/UNC-70 is essential for axon integrity in C. elegans motor neurons throughout their lifespan.

The paper identifies two conserved mechanisms controlling cytoplasmic macromolecular diffusion in C. elegans tissues, involving ribosome concentration and the giant KASH protein ANC-1.

The paper identifies kinesin-1 and RIC-7 as polarized transport complexes at the leading end of mitochondria driving anterograde axonal transport in C. elegans.