Jia Wern Pan

This study investigates how APOBEC mutagenesis and A3B deletion affect immune activation in Asian breast cancer using spatial transcriptomics, finding that mitochondrial mutations and cGAS-STING pathway activation drive immune responses instead of neoantigens.

This study analyzes the intra-tumoral microbiota in Asian breast cancer patients using bulk transcriptomic data and finds weak associations with immune scores and predictive potential using random forest models.

This study evaluates the prognostic value of immune markers in Asian breast cancer using spatial immunophenotyping and multimodal machine learning, finding that integrated spatial and molecular profiling improves prognostication.

This study identifies immune phenotype-driven clustering in HR+/HER2- breast cancer from an Asian cohort, deviating from the luminal A-luminal B classification seen in European populations.