Author

Hua Yu

City Of Hope National Medical CenterORCID 0000-0003-0931-1000Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Hua Yu2 papers · Wuhan Union Hospital

Biology Disciplines

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Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Marcin KortylewskiiD· 2 shared Aisling S. Morrin· 1 shared Alicia Derrac SoriaiD· 1 shared Ana Cardus FiguerasiD· 1 shared Antons MartincuksiD· 1 shared Anwen S. WilliamsiD· 1 shared Barbara SzomolayiD· 1 shared Benjamin C. CossinsiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersPathology

Marcin KortylewskiORCID

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2 papers

Recent·Most cited

PathologybioRxivPreprintNov 1, 2025

Discrete cytokine signaling networks instruct distinctsynovial pathotypes in inflammatory arthritis

Alicia Derrac Soria, David Gregory Hill, Stuart T. O. Hughes…·Simon A. Jones

The paper identifies distinct cytokine signaling networks in mouse models of arthritis that mirror human RA synovial pathotypes, revealing molecular mechanisms underlying disease heterogeneity.

DOI 10.1101/2025.11.01.686006

mousebulk RNA-seq

𝕏 PostBluesky

ImmunologyMolecular Therapy — Nucleic AcidsPeer-reviewedOct 9, 2024

Local CpG-Stat3 siRNA treatment improves antitumor effects of checkpoint inhibitors

Chunyan Zhang, Rui Huang, Lyuzhi Ren…·Hua Yu

This study shows that local CpG-Stat3 siRNA treatment enhances checkpoint inhibitor efficacy in mouse tumor models by improving T-cell responses.

17 citations

mouseexperimental assay

𝕏 PostBluesky