Alisha M. Block

This study shows that Mycobacterium tuberculosis needs riboflavin biosynthesis for survival during all stages of infection, suggesting it as a drug target.

This study shows that the M. tuberculosis ESX-5 secretion system is critical for growth on specific carbon sources, survival in macrophages, and replication in mice, suggesting it is a key virulence factor.

This paper identifies metabolic pathways essential for Mycobacterium tuberculosis survival during infection using transposon sequencing in a mouse model, highlighting Phe and purine/thiamine biosynthesis as potential drug targets.