Heinz Sill

This study identifies RASmutEZH2inact as a distinct CMML subgroup with increased MEK inhibitor sensitivity due to MAPK/ERK hyperactivation.

This study identifies RAS mutations as a key driver of extramedullary acute myeloid leukemia, showing their role in promoting leukemic cell migration and infiltration through the JAML-PI3K/AKT pathway.

This study identifies two genome-wide significant susceptibility loci for acute myeloid leukemia through a meta-analysis of GWAS data.

This study infers tumor cell-specific transcription factor binding from cell-free DNA to predict tumor subtypes and detect cancer early.