Author

Helen M. Ashwin

University of YorkORCID 0000-0003-1029-0032Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Microbiology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Approach:deep learning· 2 Organism:mouse· 2 Assay:spatial transcriptomics· 2 Approach:statistical model· 2 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Paul Martin KayeiD· 3 shared Grant M. Calder· 2 shared Lesley Gilbert· 2 shared Sally R. JamesiD· 2 shared Shoumit DeyiD· 2 shared Adam DowleiD· 1 shared Alastair DroopiD· 1 shared Alexander Aivazidis· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersImmunology

Paul Martin KayeORCID

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3 papers

Recent·Most cited

ImmunologyCommunications BiologyPeer-reviewedMar 20, 2026

Ontogeny-independent expression of LPCAT2 in granuloma macrophages during experimental visceral leishmaniasis

Shoumit Dey, Jianhua Cao, Benjamin Balluff…·Paul Martin Kaye

The paper uses multimodal imaging and single-cell transcriptomics to identify LPCAT2-mediated membrane remodeling in granuloma macrophages during visceral leishmaniasis.

1 citation

mousespatial transcriptomics

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MicrobiologybioRxivPreprintDec 30, 2025

Bi-directional highways and super-seeder tissues underpin parasite dissemination in experimental visceral leishmaniasis.

Ciara F. Loughrey, Juliana B. T. Carnielli, Shoumit Dey…·Paul Martin Kaye

This study maps parasite dissemination patterns in visceral leishmaniasis using a barcoded library and ecological analysis, revealing bi-directional highways and super-seeder tissues.

DOI 10.64898/2025.12.30.696984

mouseexperimental assay

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PathologyNature CommunicationsPeer-reviewedMar 10, 2025

Integrated histopathology, spatial and single cell transcriptomics resolve cellular drivers of early and late alveolar damage in COVID-19

Jimmy Tsz Hang Lee, Sam N. Barnett, Kenny Roberts…·Omer Ali Bayraktar

This study integrates single-cell and spatial transcriptomics with histopathology to identify cellular and molecular changes in lung alveolar damage during COVID-19 progression.

21 citationstop 1%

humanscRNA-seq

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