Hannelore Lotter

This study compares immune responses to pathogenic and non-pathogenic E. histolytica clones in mice, finding distinct temporal transcriptomic profiles linked to disease severity.

This study investigates sex differences in immune response to TB vaccines in mice, finding that male mice show poorer BCG vaccine efficacy and specific CD8 T cell deficiencies compared to females.

This study shows that in the absence of adaptive immunity, female mice are more susceptible to Mtb than males, highlighting a sex-based difference in innate immune responses.

This study uses spatial transcriptomics to compare aging and infection effects across multiple organs in mice, identifying shared gene expression patterns in immune pathways.

This study investigates NK cell activation by T. cruzi-infected keratinocytes and finds that NK cells are strongly activated despite minimal ligand changes, with IFN-gamma enhancing ligand expression on keratinocytes.

This study identifies two genes, ehhp127 and ehmp8-2, differentially expressed between pathogenic and non-pathogenic Entamoeba histolytica clones, showing they influence pathogenicity through distinct mechanisms.