Author
University of North Carolina at Chapel HillORCID 0000-0003-1189-6511Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Safia Mahabub Sauty, Yun-Chung Hsiao, Leszek J. Klimczak, Dmitry A. Gordenin
The paper analyzes somatic mutation profiles in normal human tissues to identify mutagenic mechanisms and their association with age, disease, and environmental exposures.
Zachary W. Kockler, Hamed Bostan, Leszek J. Klimczak…·Dmitry A. Gordenin
The paper identifies APOBEC3A as the main RNA editor in human cells and viruses, showing its preference for specific motifs in mRNA and viral RNA.
Jiahao Feng, Chih‐Wei Liu, Jingya Peng…·Kun Lü
This study shows that formaldehyde exposure alters histone methylation and acetylation in human cells, with changes resembling those in cancer and Alzheimer's disease.
Yifei Yang, Liang Chi, Yun-Chung Hsiao, Kun Lü
This study investigates sex-specific effects of gut microbiome on bile acid metabolism by transplanting feces from male and female mice and measuring bile acid profiles and gene expression.
Xing Cheng, Jing An, Jitong Lou…·Yang Yang
This study identifies RAD18's role in TMZ resistance and hypermutation in GBM by linking it to TLS and MMR pathways through CRISPR screening and mutation analysis.