Author

Jane Macnaughtan

Aligning Science Across Parkinson'sORCID 0000-0003-1211-9298Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Animal Behavior & Cognition· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Anthony H.V. SchapiraiD· 2 shared Elisa MenozziiD· 2 shared Kai‐Yin ChauiD· 2 shared Sofia KoletsiiD· 2 shared Abeba HabtesioniD· 1 shared Alexandra PhillipsiD· 1 shared Alexandre FamechoniD· 1 shared Aymeric DavidiD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersNeuroscience

Anthony H.V. SchapiraORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

NeuroscienceFrontiers in NeurosciencePeer-reviewedOct 1, 2025

Exploring the relationship between GBA1 host genotype and gut microbiome in the GBA1L444P/WT mouse model: Implications for Parkinson disease pathogenesis

Elisa Menozzi, Mallia Geiger, Victoria Meslier…·Anthony H.V. Schapira

This study investigates whether GBA1 heterozygosity affects gut microbiome composition in a mouse model, finding no significant differences between genotypes.

3 citations

mousemetagenomics

𝕏 PostBluesky

Animal Behavior & CognitionbioRxivPreprintAug 15, 2023

Impact of Yaq-001, a non-absorbable, engineered carbon bead of controlled porosity in rodent models of cirrhosis and acute on chronic liver failure

Jinxia Liu, Jane Macnaughtan, Yi Jin…·Rajiv Jalan

This study evaluates Yaq-001, a non-absorbable carbon bead, in rodent cirrhosis and ACLF models, showing improvements in inflammation, liver function, and microbiome composition.

DOI 10.1101/2023.08.15.553396

ratmetabolomics

𝕏 PostBluesky

NeuroscienceBrain CommunicationsPeer-reviewedJan 1, 2023

α-synuclein expression in response to bacterial ligands and metabolites in gut enteroendocrine cells

Michael J. Hurley, Elisa Menozzi, Sofia Koletsi…·Anthony H.V. Schapira

This study shows bacterial ligands and metabolites increase α-synuclein levels in gut enteroendocrine cells, potentially contributing to Parkinson's disease pathology.

22 citations

mousebulk RNA-seq

𝕏 PostBluesky