Federico Nicolás Soria

This study shows that oligodendroglial dysfunction in an ASD model leads to hypomyelination, circuit dysfunction, and social deficits, with early treatment restoring these features.

This study investigates how reperfusion affects neurovascular injury after ischemic stroke, finding that while it reduces acute damage, it leads to chronic vascular dysfunction.

This study identifies MYRF dysregulation as a mechanism linking Aβ pathology to oligodendrocyte and cognitive impairments in Alzheimer's disease, showing that PKC inhibition can restore myelin and cognition.

The paper identifies Thbs4-positive astrocytes from the SVZ that modulate the extracellular matrix at the glial scar after brain ischemia by synthesizing and degrading hyaluronan.

This paper introduces a viral-mediated fluorescent probe to label hyaluronan in the mouse brain, enabling real-time imaging of extracellular matrix dynamics in vivo.

This study shows that IRF5 regulates microglial myelin clearance and cholesterol metabolism after demyelination, with implications for remyelination in multiple sclerosis.

This study shows that microglial phagocytosis dysfunction during stroke is prevented by rapamycin, highlighting its potential as a therapeutic target.

This study shows that amyloid beta oligomers impair autophagy in neurons via the primary cilium, with age-dependent effects mediated by Akt and p75NTR.