Author

Julien Roche

Iowa State UniversityORCID 0000-0003-1254-1173Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Abhishek KumariD· 1 shared Alexandar L. HanseniD· 1 shared Alexandre Desgranges· 1 shared Amy Hamilton AndreottiiD· 1 shared Blanton S. TolbertiD· 1 shared D. Bruce Fulton· 1 shared David Yin-wei LiniD· 1 shared Davit A. PotoyaniD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBiochemistry

Abhishek KumarORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

GeneticsbioRxivPreprintOct 19, 2026

The usefulness of triploid sib records for selection of diploid candidates in rainbow trout breeding programs for growth, processing traits and hypoxia tolerance

Julien Roche, Lou Buisson, Pierre Patrice…·Florence Phocas

This study evaluates using triploid sib records to improve diploid selection in rainbow trout breeding for growth, processing traits, and hypoxia tolerance, finding high genetic correlations and benefits for certain traits.

DOI 10.64898/2026.10.18.759899

statistical model

𝕏 PostBluesky

BiochemistrybioRxivPreprintOct 17, 2026

BTK dynamics and function are differentially influenced by distinct covalent inhibitor warhead chemistries.

Raji E. Joseph, Robert G. Britton, David Yin-wei Lin…·Amy Hamilton Andreotti

This study compares the effects of different warhead chemistries in covalent inhibitors on BTK dynamics and function, showing that 2-butynamide induces conformational heterogeneity and reduced efficacy compared to acrylamide.

DOI 10.64898/2026.05.07.723540

humanexperimental assay

𝕏 PostBluesky

BiochemistryScience AdvancesPeer-reviewedJul 10, 2024

Thermodynamic Coupling of the tandem RRM domains of hnRNP A1 underlie its Pleiotropic RNA Binding Functions

Jeffrey D. Levengood, Davit A. Potoyan, Srinivasa R. Penumutchu…·Blanton S. Tolbert

This study shows that thermodynamic coupling between tandem RRM domains of hnRNP A1 is essential for its allosteric RNA binding functions and stability under pressure.

12 citations

protein structureexperimental assay

𝕏 PostBluesky