Author

Daan Gilissen

HAN University of Applied SciencesORCID 0000-0003-1465-3400Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Anja Krippner‐HeidenreichiD· 1 shared Bert A. van der ReijdeniD· 1 shared Branco M. H. HeutsiD· 1 shared Christian GilisseniD· 1 shared Coos A. B. BaakmaniD· 1 shared Gerrit Vriend· 1 shared Joop H. JanseniD· 1 shared Joost H.A. MartensiD· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

Anja Krippner‐HeidenreichORCID

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2 papers

Recent·Most cited

Cancer BiologyLeukemiaPeer-reviewedDec 4, 2024

The neuronal homeobox transcription factor HMX3 is a crucial vulnerability factor in MECOM-negative KMT2A::MLLT3 acute myelomonocytic leukemia

Saioa Arza-Apalategi, Branco M. H. Heuts, Saskia M. Bergevoet…·Bert A. van der Reijden

The paper identifies HMX3 as a critical vulnerability in MECOM-negative KMT2A::MLLT3 AML, showing it promotes proliferation and blocks differentiation.

4 citations

humanbulk RNA-seq

𝕏 PostBluesky

BioinformaticsHuman MutationPeer-reviewedMay 22, 2019

MetaDome: Pathogenicity analysis of genetic variants through aggregation of homologous human protein domains

Laurens Wiel, Coos A. B. Baakman, Daan Gilissen…·Christian Gilissen

MetaDome provides a web service to analyze genetic variants by aggregating homologous human protein domains, improving interpretation of variants of unknown significance.

264 citationstop 1%

humanDNA methylation

𝕏 PostBluesky