Michelle A. E. Anderson

The paper develops and validates an SDA-500 Anopheles stephensi cell line for molecular studies, showing it supports efficient transgene expression and functional genomics research.

The paper investigates fitness differences between knock-in and knock-out cd mutants in Anopheles stephensi, finding that knock-in mutants have reduced survival and midgut dysfunction, while knock-outs do not.

The paper assesses two multiplexing strategies for CRISPR/Cas9-based gene drives in Anopheles stephensi to overcome target site resistance.

The paper shows that varying the length of the AePUb promoter in Aedes aegypti can adjust reporter gene expression levels in both cell culture and mosquitoes.

This paper improves genetic manipulation techniques in Aedes aegypti by introducing transgenic lines for Cre-mediated recombination and a plasmid-based PhiC31 integrase system for stable transgene integration.

The paper develops a synthetic biology approach to modulate gene expression in mosquitoes by systematically characterizing modifications in translation initiation sequences and 3' UTRs.

This study investigates inheritance bias mechanisms in a CRISPR gene drive in Aedes aegypti, finding two distinct mechanisms: homing in double heterozygous males and meiotic drive.

The paper identifies small silencing RNAs targeting PxyMasc, a male-determining gene in diamondback moth, expressed from W-linked retrocopies on the female-specific chromosome.

This study tests a CRISPR/Cas9 split-drive system in the diamondback moth, showing high somatic editing but limited germline activity.

This study shows that the Nix gene can convert female Aedes aegypti mosquitoes into fertile males, which can then produce sex-converted offspring, but require mating with wild-type females to fly, and myo-sex is essential for male flight.