Oliver J. Harrison

This study shows that B cell v integrin limits GC activity and memory B cell expansion in the lung after IAV infection, suggesting it as a target for improving mucosal vaccines.

The paper identifies a commensal-specific CD8αβ+ T cell population in the intestine driven by a single commensal species and shows how epithelial signals regulate their differentiation and restraint.

This study shows UC-associated autoantibodies to αvβ6 inhibit mucosal TGFβ activation, disrupt epithelial homeostasis, and increase susceptibility to intestinal inflammation.

This study identifies HIF2 as a key regulator of Th2 cell differentiation and function in the small intestine during helminth infection.

This study shows that type 1 immunity, via IFNγ signaling, protects intestinal tissue from damage during helminth infection without reducing parasite burden.

This study identifies SFB-specific B cell responses using phage display and tetramers, revealing compartmentalized activation and isotype gradients in the gut.

This study identifies a neuroimmune CGRP-RAMP1 axis that modulates cutaneous adaptive immunity to the microbiota by constraining Type 17 responses and limiting T cell activation.