NeurosciencebioRxivPreprint
A coronavirus protease activates sensory neurons via TRPA1 to drive sneeze, cough, and pain
Sonali S. Mali, Ricardo Silva, Zhongyan Gong…·Diana M. Bautista
This study shows that SARS-CoV-2's PLpro protease activates sensory neurons via TRPA1, causing sneezing, coughing, and pain, and identifies these as potential therapeutic targets.