Katja C. Wolthers

This study identifies metabolic changes and glutamate excitotoxicity in HPeV-3 infected neural organoids, linking them to neuronal toxicity and apoptosis.

This paper develops a human intestinal mucosa model incorporating epithelial, fibroblast, and antigen-presenting cells to study intestinal development and disease mechanisms.

This study investigates epithelial responses to commensal and pathogenic bacteria using intestinal models, showing differences in immune activation between cell lines and organoids.

This study evaluates the antiviral efficacy of halofuginone hydrobromide against multiple viruses in human organoid models, finding it effective only against SARS-CoV-2.