Author

Pamela E. Capendale

Amsterdam UMC Location University of AmsterdamORCID 0000-0003-1773-9453Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:organoid / primary culture· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Adithya SridhariD· 2 shared Dasja PajkrtiD· 2 shared Inés García-RodrígueziD· 2 shared Katja C. WolthersiD· 2 shared Renata Vieira de SáiD· 2 shared Anoop T. AmbikaniD· 1 shared Carlemi CalitziD· 1 shared Eline Freeze· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersNeuroscience

Adithya SridharORCID

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2 papers

Recent·Most cited

NeuroscienceCellular and Molecular Life SciencesPeer-reviewedNov 5, 2025

Parechovirus-3 infection disrupts immunometabolism and leads to glutamate excitotoxicity in neural organoids

Pamela E. Capendale, Anoop T. Ambikan, Inés García-Rodríguez…·Adithya Sridhar

This study identifies metabolic changes and glutamate excitotoxicity in HPeV-3 infected neural organoids, linking them to neuronal toxicity and apoptosis.

3 citations

humanproteomics

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MicrobiologyAntiviral ResearchPeer-reviewedJan 6, 2024

Assessment of The Broad-Spectrum Host Targeting Antiviral Efficacy of Halofuginone Hydrobromide in Human Airway, Intestinal and Brain Organoid Models.

Inés García-Rodríguez, Giulia Moreni, Pamela E. Capendale…·Carlemi Calitz

This study evaluates the antiviral efficacy of halofuginone hydrobromide against multiple viruses in human organoid models, finding it effective only against SARS-CoV-2.

9 citations

humanorganoid / primary culture

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