Alessandro Gori

This study uses AI to design a peptide inhibitor of WWP1, showing potent activity against breast cancer, especially TNBC, with promising cytotoxic effects and synergistic potential with PI3K inhibitors.

This paper introduces a membrane-sensing peptide-based method for isolating urinary extracellular vesicles, showing improved purity, reduced contaminants, and better scalability compared to traditional methods.

This paper develops a peptidomimetic inhibitor of eIF4E that suppresses cap-dependent translation in cancer and neurodevelopmental disorders, showing efficacy in cell and animal models.

This paper introduces an enhanced SiMoA platform using membrane sensing peptides to detect HER2 on extracellular vesicles in metastatic breast cancer patients, showing improved sensitivity and prognostic relevance.

This paper introduces Membrane-Sensing Peptides (MSP) as universal affinity ligands for analyzing Extracellular Vesicles and analogues, demonstrating their ability to detect EV-associated epitopes in clinical samples without prior isolation.