Pharmacology & ToxicologyRedox BiologyPeer-reviewed
Small molecule nitroalkenes inhibit RAD51-mediated homologous recombination and amplify triple-negative breast cancer cell killing by DNA-directed therapies.
Lisa T. Hong, Dennis Braden, Yaoning Zhao…·Carola Anke Neumann
This paper identifies nitroalkenes that inhibit RAD51-mediated homologous recombination, enhancing DNA damage in triple-negative breast cancer cells and showing potential as anticancer agents.
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