Adam C. Straub

The paper compares the ability of different Orai isoforms to promote NFAT activation and transcription, finding Orai1α and Orai1β are more potent than Orai2 and Orai3.

This study shows that Mitoregulin (Mtln) protects mitochondrial membrane integrity and reduces cardiac ischemia-reperfusion injury by stabilizing cardiolipin and preventing membrane damage.

This study shows CYB5R3 is essential for stress-induced erythropoiesis, with stronger effects in males, and reveals its role in heme biosynthesis and erythroid differentiation.

This paper identifies CYB5R3 as a redox switch that couples store-operated calcium entry to TRPV2 activation, enhancing vascular function through NO-dependent oxidative inhibition of PTPN1.

This study identifies CYB5R4 as a regulator of endothelial proliferation and ischemia-induced angiogenesis through RRM2-dependent nucleotide balance.

The paper develops HemoLens, a low-cost open-source pressure myography system for characterizing vascular mechanics in native and engineered blood vessels.

This paper identifies nitroalkenes that inhibit RAD51-mediated homologous recombination, enhancing DNA damage in triple-negative breast cancer cells and showing potential as anticancer agents.