Author

Rudolf J. Wiesner

University of CologneORCID 0000-0003-1677-4476Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Andre Ferrer CarvalhoiD· 1 shared Bent BrachvogeliD· 1 shared Bernd NeumaieriD· 1 shared Britta EggersiD· 1 shared Carolin Berwanger· 1 shared Christoph Stephan ClemeniD· 1 shared Dominic Terres· 1 shared Dominik Hans PestaiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Andre Ferrer CarvalhoORCID

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2 papers

Recent·Most cited

Cell BiologyEuropean Journal of Cell BiologyPeer-reviewedFeb 20, 2024

Immortalised murine R349P desmin knock-in myotubes exhibit a reduced proton leak and decreased ADP/ATP translocase levels in purified mitochondria

Carolin Berwanger, Dominic Terres, Dominik Hans Pesta…·Christoph Stephan Clemen

This paper establishes an immortalised murine desminopathy model and finds reduced mitochondrial proton leak and ADP/ATP translocase levels in desminopathy myotubes.

3 citations

mouseproteomics

𝕏 PostBluesky

NeurosciencebioRxivPreprintJul 7, 2023

Preserved striatal innervation and motor function despite severe loss of nigral dopamine neurons following mitochondrial dysfunction induced by mtDNA mutations

Thomas Paß, Konrad M. Ricke, Pierre Hofmann…·Rudolf J. Wiesner

This study shows that mice with severe loss of nigral dopamine neurons due to mtDNA mutations still maintain motor function through preserved striatal innervation.

2 citations

mousebulk RNA-seq

𝕏 PostBluesky