Yotam Drier

This study identifies a CTCF-binding insulator element that regulates receptor editing and B-cell tolerance by controlling chromatin loop extrusion and Ig{lambda} development.

This study identifies DSB patterns in BRCAmut carriers to reveal early oncogenic processes linked to HR deficiency.

This study uses scRNA-seq to analyze HPV-related multiphenotypic sinonasal carcinoma and finds an association between HPV and MYB expression, with potential prognostic implications.

This study identifies three regulatory subtypes of lung neuroendocrine tumors through ChIP-seq and RNA-seq, revealing distinct transcription factor signatures and therapeutic vulnerabilities.

The paper introduces SiPSiC, a method to estimate pathway activity in single cells, enabling more sensitive differential analysis and clustering, with applications in disease studies.

This study shows SMCHD1 loss causes DUX4 expression in FSHD2 by disrupting splicing of DNMT3B, leading to hypomethylation and muscle abnormalities.

This study investigates the roles of TAL1 isoforms in hematopoiesis and cell growth, finding that TAL1-short promotes apoptosis and can act as a tumor suppressor.